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SU6656
CAS No. : 330161-87-0
MCE 国际站:SU6656
产品活性:SU6656 是 Src 家族激酶抑制剂,抑制 Src,Yes,Lyn,Fyn 的 IC50分别为 280,20,130,170 nM。SU6656 可抑制 FAK Y576/577、 Y925、Y861 位点的磷酸化。SU6656 还能抑制p-AKT。
研究领域:Protein Tyrosine Kinase/RTK | PI3K/Akt/mTOR
In Vitro: SU6656 decreases phosphorylation of Src family kinases (SFKs) in HNSCC cells.
In Vivo: SU6656 (2-4 mg/kg; i.p.; once) significantly decreases ischemic postconditioning (IPoCo) mediated increase in fall down time.
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