Iterative Crystallography Service：Chloride intracellular channel 4
产品名称： Iterative Crystallography Service：Chloride intracellular channel 4
英文名称： Iterative Crystallography Service：Chloride intracellular channel 4
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http://www.creative-biostructure.com/Iterative-crystallography/Iterative-crystallography-CBCRY20.htm
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Cat. No. |
CBCRY20 |
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Background |
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). |
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Molecular description |
Protein Classification |
Transport protein |
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Structure Weight |
89641.50 Da |
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Polymer |
1 |
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Molecule |
Chloride intracellular channel protein 4 |
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Chain Length |
261 amino acids |
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Crystal Description |
PDB ID |
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MMDB ID |
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Source |
E.coli |
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Method |
X-Ray Diffraction |
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Resolution |
2.8Å |
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Gene information |
Gene Name |
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Synonyms |
CLIC4L; DKFZp566G223; FLJ38640; H1; MTCLIC; huH1; p64H1; OTTHUMP00000003380; chloride intracellular channel 4 like; Intracellular chloride ion channel protein p64H1 |
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UniProt ID |
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GeneID |
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Chromosome Location |
1p36.11 |
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Function |
chloride ion binding; protein binding; voltage-gated chloride channel activity; voltage-gated ion channel activity. |
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Reference |
Li, Y.F., Li, D.F., Zeng, Z.H., Wang, D.C. (2006) Trimeric structure of the wild soluble chloride intracellular ion channel CLIC4 observed in crystals Biochem.Biophys.Res.Commun. 343: 1272-1278 |
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