FITC标记的扁豆凝集素
产品名称: FITC标记的扁豆凝集素
英文名称: Anti-Lens culinaris agglutinin/FITC
产品编号: HZ-6439R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-Lens culinaris agglutinin/FITC Conjugated antibody
FITC标记的扁豆凝集素
产品编号 | bs-6439R-FITC |
英文名称 | Anti-Lens culinaris agglutinin/FITC |
中文名称 | FITC标记的扁豆凝集素 |
别 名 | LCA/Lens culinaris agglutinin; LEC_LENCU. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Lens culinaris (lentil) |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 27kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from Lens culinaris agglutinin |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are engulfed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. Although LCA and LCB are encoded by two discrete genes sharing only 60% homology, they have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms. Additionally, in the brain, LCA and LCB contain inserted sequences that form higher molecular weight isoforms. These sequences insert at similar cytoplasmic domain encoding regions for both LCA and LCB. Similarity: Belongs to the leguminous lectin family. Database links:
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
网格蛋白是一种主要的胞浆外壳蛋白,来源于质膜和跨高尔基网络的小窝和囊泡。在受体介导的内吞作用中,受体蛋白被网格蛋白包被囊泡吞噬。网格蛋白由三个重链和三个轻链组成,它们与非共价缔合形成三叉结构。网格蛋白轻链调节三重离子自组装到细胞膜上。网格蛋白轻链亚单位(LCA和LCB)有助于调节包囊形成,以在受体介导的内吞作用和细胞器生物合成过程中对蛋白质进行分类。虽然LCA和LCB由两个仅共享60%同源性的离散基因编码,但它们具有共同的某些特征。LCA和LCB都经历选择性mRNA剪接,这导致组织特异性亚型的产生。此外,在大脑中,LCA和LCB包含形成较高分子量异构体的插入序列。这些序列插入类似的细胞质域编码区域的LCA和LCB。