FITC标记的精子线粒体相关富含半胱氨酸蛋白抗体
产品名称： FITC标记的精子线粒体相关富含半胱氨酸蛋白抗体
英文名称： Anti-SMCP/FITC
产品编号： HZ-20082R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SMCP/FITC Conjugated antibody
FITC标记的精子线粒体相关富含半胱氨酸蛋白抗体
| 英文名称 | Anti-SMCP/FITC |
| 中文名称 | FITC标记的精子线粒体相关富含半胱氨酸蛋白抗体 |
| 别 名 | HSMCSGEN1; MCS; MCSP; MCSP_HUMAN; Mitochondrial capsule selenoprotein; SMCP; Sperm mitochondria associated cysteine rich protein; Sperm mitochondrial-associated cysteine-rich protein. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 干细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 13kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SMCP |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SMCP is a 116 amino acid cytoplasmic protein that is found in the outer capsule that is associated with sperm mitochondria. Expressed specifically in spermatids of seminiferous tubules, SMCP is thought to be involved in the organization and stabilization of the helical sheath structure and may play a role in overall sperm motility. SMCP has a short N-terminal segment, a C-terminal lysine and several internal cysteines. Defects in the gene encoding SMCP may be a cause of male infertility due to both reduced sperm motility and an inability to pierce the zona pellucida of the female egg. Function: Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida. Subcellular Location: Cytoplasm. Mitochondrion membrane. Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis. Tissue Specificity: Testis. Is selectively expressed in the spermatids of seminiferous tubules. Database links: Entrez Gene: 4184 Human Omim: 601148 Human SwissProt: P49901 Human Unigene: 111850 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SMCP是在与精子线粒体相关的外囊中发现的一种116氨基酸胞质蛋白。SMCP特异表达于生精小管的精子中，被认为参与螺旋鞘结构的组织和稳定，并可能在整个精子运动中发挥作用。SMCP有一个短的N-末端片段，一个C-末端赖氨酸和几个内部半胱氨酸。编码SMCP的基因的缺陷可能是由于精子活动性降低和无法穿透雌性卵子的透明带而导致男性不育的原因。