FITC标记的微管动力调节蛋白FAM82A抗体
产品名称： FITC标记的微管动力调节蛋白FAM82A抗体
英文名称： Anti-FAM82A1/FITC
产品编号： HZ-8312R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-FAM82A1/FITC Conjugated antibody
FITC标记的微管动力调节蛋白FAM82A抗体
| 产品编号 | bs-8312R-FITC |
| 英文名称 | Anti-FAM82A1/FITC |
| 中文名称 | FITC标记的微管动力调节蛋白FAM82A抗体 |
| 别 名 | BLOCK18; FAM82A; Fam82a1; Family with sequence similarity 82 member A; Family with sequence similarity 82, member A1; hRMD 2; hRMD 4; hRMD-2; hRMD4; MGC33318; Microtubule associated protein; Protein FAM82A1; Regulator of microtubule dynamics; Regulator of microtubule dynamics protein 2; RMD 2; RMD-2; RMD2; RMD2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FAM82A1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The FAM82A gene product has been provisionally designated FAM82A pending further characterization. Subunit: Interacts with microtubules. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles. Also detected as large dots in the perinuclear region. Similarity: Belongs to the FAM82/RMD family. Database links: Entrez Gene: 151393 Human Omim: 611872 Human SwissProt: Q96LZ7 Human Unigene: 591566 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
第二大人类染色体，2由2亿3700万个碱基组成，编码超过1400个基因，约占人类基因组的8%。许多遗传疾病与2号染色体上的基因有关。丑角鳞癣，一种罕见的病态皮肤畸形，与ABCA12基因突变有关。脂类代谢紊乱是与ABCG5和ABCG8相关的。ALSTR综合征是一种极为罕见的隐性遗传性疾病，其原因在于ALMS1基因的突变。有趣的是，第2号染色体似乎是残留的第二着丝粒和残留的端粒，这证明了人类2号染色体是古代猿类的两种祖先染色体的古老融合的结果。FAM82A基因产物已暂时指定为FAM82A，有待进一步鉴定。