FITC标记的原癌基因CD39样蛋白4/ENTPD5抗体
产品名称： FITC标记的原癌基因CD39样蛋白4/ENTPD5抗体
英文名称： Anti-CD39L4/FITC
产品编号： HZ-6526R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-CD39L4/FITC Conjugated antibody
FITC标记的原癌基因CD39样蛋白4/ENTPD5抗体
| 英文名称 | Anti-CD39L4/FITC |
| 中文名称 | FITC标记的原癌基因CD39样蛋白4/ENTPD5抗体 |
| 别 名 | CD39 like 4; AI196558; AI987697; CD39 antigen like 4; CD39 antigen-like 4; CD39 like 4; CD39L4; Ectonucleoside triphosphate diphosphohydrolase 5; ENTP5_HUMAN; Entpd5; ER UDPase; ER-UDPase; GDPase ENTPD5; Guanosine-diphosphatase ENTPD5; MGC163357; MGC163359; mNTPase; NTPDase 5; Nucleoside diphosphatase; PCPH; Pcph proto oncogene protein; Proto oncogene CPH; UDPase ENTPD5; Uridine-diphosphatase ENTPD5 |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 染色质和核信号 信号转导 肿瘤细胞生物标志物 新陈代谢 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ENTPD5/CD39L4 (331-380aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases. Function: Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling Subcellular Location: Endoplasmic reticulum membrane, Single-pass type II membrane protein Tissue Specificity: Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues. Post-translational modifications: N-glycosylated; high-mannose type Similarity: Belongs to the GDA1/CD39 NTPase family. Database links: Entrez Gene: 957 Human Entrez Gene: 12499 Mouse Entrez Gene: 314312 Rat Omim: 603162 Human SwissProt: O75356 Human SwissProt: Q9WUZ9 Mouse SwissProt: Q6P6S9 Rat Unigene: 720540 Human Unigene: 10211 Mouse Unigene: 63533 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质类似于E型核苷酸酶（NTPase）/ECTO ATPase / APYRase。NTPASs，如CD39，介导细胞外核苷酸的分解代谢。EtPD5包含4个ApRRASE保守区，这是NTPASs的特征。