FITC标记的溶质载体家族蛋白35成员D2抗体
产品名称： FITC标记的溶质载体家族蛋白35成员D2抗体
英文名称： Anti-SLC35D2/FITC
产品编号： HZ-19824R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SLC35D2/FITC Conjugated antibody
FITC标记的溶质载体家族蛋白35成员D2抗体
| 英文名称 | Anti-SLC35D2/FITC |
| 中文名称 | FITC标记的溶质载体家族蛋白35成员D2抗体 |
| 别 名 | Fringe connection; HFRC 1; Hfrc; HFRC1; Homolog of Fringe connection protein 1; MGC117215; MGC142139; Nucleotide sugar transporter UGTrel8; S35D2_HUMAN; SLC35D2; Solute carrier family 35 member D2; SQV 7L; SQV7-like protein; SQV7L; UDP N acetylglucosamine transporter; UDP-galactose transporter-related protein 8; UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; UGTrel 8; UGTrel8. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 37kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC35D2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar transporters, such as SLC35D2 (Suda et al., 2004 [PubMed 15082721]).[supplied by OMIM, Mar 2008] Function: Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Highly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus. Similarity: Belongs to the TPT transporter family. SLC35D subfamily. Database links: Entrez Gene: 11046 Human Omim: 609182 Human SwissProt: Q76EJ3 Human Unigene: 494556 Human Unigene: 731624 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
核苷酸糖是在细胞质或细胞核中合成的，是位于内质网和高尔基体腔内的糖基转移酶的高能供体底物。核苷酸糖从细胞质转运到腔室是由特定的核苷酸糖转运体介导的，例如SLC35D2(Suda等人，2004[PubMed 15082721])。