重组人羧肽酶B2(CPB2)
产品名称: 重组人羧肽酶B2(CPB2)
英文名称: Recombinant Human Carboxypeptidase B2
产品编号: HZ1741
产品价格: 0
产品产地: 中国/上海
品牌商标: 沪震生物
更新时间: 2023-08-17T10:24:20
使用范围: null
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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重组人羧肽酶B2(CPB2)
中文名称:重组人羧肽酶B2(CPB2)
英文名称:Recombinant Human Carboxypeptidase B2
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe23-Val423在C端含有His标签。
CPB2质量控制:>95%(还原性SDS-PAGE)
CPB2制剂:液体
CPB2保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于CPB2:
Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the plasma as a plasminogen-bound zymogen. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides, such as kinins or anaphylatoxins, in the circulation regulating their activities. CPB2 also down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. CPB2 exhibits carboxypeptidase activity when it is activated by proteolysis at residue Arg92 of the thrombin/thrombomodulin complex. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
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