FITC标记的KIAA2026蛋白抗体
产品名称： FITC标记的KIAA2026蛋白抗体
英文名称： Anti-KIAA2026/FITC
产品编号： HZ-17038R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-KIAA2026/FITC Conjugated antibody
FITC标记的KIAA2026蛋白抗体
| 英文名称 | Anti-KIAA2026/FITC |
| 中文名称 | FITC标记的KIAA2026蛋白抗体 |
| 别 名 | K2026_HUMAN; KIAA2026; Uncharacterized protein KIAA2026. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 228kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIAA2026 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: KIAA2026 is a 2,103 amino acid protein that exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9p24.1. Consisting of about 145 million bases, chromosome 9 makes up approximately 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. Database links: Entrez Gene: 158358 Human SwissProt: Q5HYC2 Human Unigene: 535060 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
KIAA2026是一种2103个氨基酸的蛋白质，以两种可选择的剪接异构体存在，并且由映射到人类染色体9p24.1的基因编码。由约1亿4500万个碱基组成，9号染色体约占人类基因组的4%，编码近900个基因。被认为在性别决定中起作用，9p末端的缺失可导致男女性反转，即具有男性X，Y基因型的女性的表型。遗传性出血性毛细血管扩张症以有害的血管缺陷为特征，与编码内皮素蛋白的9号染色体基因ENG相关。家族性自主神经障碍也通过IKBKAP基因与9号染色体相关。值得注意的是，9号染色体包含最大的干扰素家族基因簇。染色体9与染色体22一起参与易位，导致白血病中常见的BCR-ABL融合蛋白的异常产生。