重组小鼠IL-11-RNAi技术-试剂-生物在线
上海沪震实业有限公司
重组小鼠IL-11

重组小鼠IL-11

商家询价

产品名称： 重组小鼠IL-11

英文名称： Recombinant Murine Interleukin-11

产品编号： HZ4477

产品价格： 0

产品产地： 中国/上海

品牌商标： 沪震生物

更新时间： 2023-08-17T10:24:20

使用范围： null

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 重组小鼠IL-11

中文名称：重组小鼠IL-11
英文名称：Recombinant Murine Interleukin-11
产品规格：2μg
分子量：Approximately 19.1kDa,a single non-glycosylated polypeptide chain containing 179 amino acids.
储存条件：冷冻（-20℃）

概述

Interleukin-11(IL-11)is encoded by the IL11 gene.IL-11 is a multifunctional cytokine first isolated from bone marrow-derived stromal cells.IL-11 receptor activation requires formation of a complex of two IL-11 molecules with two molecules of the ligand-binding IL-11 Rα subunit and two molecules of the expressed cell signaling β subunit,gp130.IL-11 is a member of the IL-6 superfamily,distinguished based on their use of the common co-receptor gp130.IL-11 can directly stimulate the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells,and induce megakaryocyte maturation resulting in increased platelet production.Mature murine IL-11 shares 88%amino acid sequence identity with human IL-11.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观 Sterile Filtered White lyophilized(freeze-dried)powder.
纯度 ＞97%by SDS-PAGE and HPLC analyses.
来源 Escherichia coli.
生物活性 Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine T11 cells is less than 2ng/ml,corresponding to a specific activity of>5.0×105 IU/mg.
成分 Lyophilized from a 0.2μmfiltered solution in PBS,pH 7.4.
内毒素 Less than 1 EU/μg of rMuIL-11 as determined by LAL method.
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列 MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDHSLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLKTLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGSIRAAHAILGG LHLTLDWAVR GLLLLKTRL

 

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！