FITC标记的SNF1/AMP激酶相关激酶2抗体
产品名称: FITC标记的SNF1/AMP激酶相关激酶2抗体
英文名称: Anti-NUAK2/FITC
产品编号: HZ-5811R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-NUAK2/FITC Conjugated antibody
FITC标记的SNF1/AMP激酶相关激酶2抗体
英文名称 | Anti-NUAK2/FITC |
中文名称 | FITC标记的SNF1/AMP激酶相关激酶2抗体 |
别 名 | NUAK family SNF1 like kinase 2; NUAK family SNF1-like kinase 2; Nuak2; NUAK2_HUMAN; SNARK; SNF1/AMP activated protein kinase; SNF1/AMP kinase related kinase; SNF1/AMP kinase-related kinase. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 免疫学 信号转导 细胞凋亡 激酶和磷酸酶 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 70kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NUAK2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. Database links: Entrez Gene: 81788 Human Entrez Gene: 74137 Mouse Omim: 608131 Human SwissProt: Q9H093 Human SwissProt: Q8BZN4 Mouse Unigene: 497512 Human Unigene: 100666 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
应激激活的激酶参与葡萄糖饥饿的耐受性。通过增加F-肌动蛋白转化为G-肌动蛋白诱导细胞分裂。通过CD95或TNF-α诱导表达,通过NF-kAPA- B保护细胞免受CD95介导的细胞凋亡,并且对CD95活化的肿瘤细胞的运动性和侵袭性的增强是必需的。