重组人粒细胞集落刺激因子
产品名称: 重组人粒细胞集落刺激因子
英文名称: Recombinant Human Granulocyte Colony Stimulating Factor
产品编号: 102-02
产品价格: 0
产品产地: 美国
品牌商标: sciencell
更新时间: 2024-11-06T10:04:08
使用范围: null
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ScienCell研究实验室生产的原代细胞、原代细胞专用培养基都经过了严格的质量控制,细胞纯度可达98%。其中包括21种人体正常细胞系统,90多种不同细胞类型。大多数细胞在全球唯有ScienCell实验室能够成功分离,产品质量过硬。确保了实验结果的重复性和连贯性。
Description | G-CSF is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation, and activation of hematopoietic cells of the neutrophilic granulocyte lineage. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNF-a and IFN-g. Other cell types including fibroblasts, endothelial cells, astrocytes and bone marrow stromal cells can also secrete G-CSF after LPS, IL-1 or TNF-a activation. In addition, various carcinoma cell lines and myeloblastic leukemia cells can express G-CSF constitutively. In humans, two distinct cDNA clones for G-CSF, encoding 207 and 204 amino acid precursor proteins, have been isolated. Both proteins have a 30 amino acid signal peptide and have identical amino acid sequences except for a three amino acid insertion (deletion) at the 35th amino acid residue from the N-terminus of the mature protein. Human G-CSF is 73% identical at the amino acid level to murine G-CSF and the two proteins show species cross-reactivity. |
Synonyms | CSF-3, MGI-1G, GM-CSF beta, Pluripoietin, Filgrastim, Lenograstim, G-CSF, MGC45931, GCSF, CSF3OS; C17orf33 |
AA Sequence | TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP |
Source | Escherichia coli |
Molecular Weight | Approximately 18.7 kDa, a single non-glycosylated polypeptide chain containing 174 amino acids. |
Biological Activity | Fully biologically active. The ED50 is < 0.1 ng/ml, corresponding to a specific activity of 1 x 10^8 units/mg, as determined by murine NFS-60 indicator cell proliferation. |
Physical Appearance | White lyophilized powder. |
Formulation | Lyophilized from a 0.2μm filtered concentrated (1mg/ml) solution in 10mM sodium acetate buffer pH 4.0. |
Endotoxin | < 1EU/μg of growth factor as determined by LAL method. |
Reconstitution | Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |
Storage | Store at -20°C after receiving. Upon Reconstitution, store at 2-8°C for up to one week. For maximal stability, aliquot and store at -20°C. Avoid repeated freeze/ thaw cycles. |
Usage | This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. |
Growth Factors and Cytokines
Human Growth Factors
102-01
rhSCF
重组人干细胞因子
Recombinant Human Stem Cell Factor
2µg
102-02
rhG-CSF
重组人粒细胞集落刺激因子
Recombinant Human Granulocyte Colony Stimulating Factor
2µg
102-03
rhGM-CSF
重组人粒细胞巨噬细胞集落刺激因子
Recombinant Human Granulocyte Macrophage Colony Stimulating Factor
5µg
102-09
rhM-CSF
重组人巨噬细胞集落刺激因子
Recombinant Human Macrophage Colony Stimulating Factor
2µg
103-01
rhTNF-α
重组人肿瘤坏死因子-α
Recombinant Human Tumor Necrosis Factor-alpha
10µg
103-01H
rhTNF-α-His
重组人肿瘤坏死因子-α,His
Recombinant Human Tumor Necrosis Factor-alpha,His
10µg
103-01V
rhTNF-α Vari
重组人肿瘤坏死因子-αVariant
Recombinant Human Tumor Necrosis Factor- alpha Variant
10µg
103-04
rhBAF
重组人B细胞活化因子
Recombinant Human B Cell Activating Factor
5µg
103-08
rhOSM
重组人抑瘤素-M
Recombinant Human Oncostatin-M
2µg
103-08T
rhOSM 209a.a.
重组人抑瘤素-M209a.a.
Recombinant Human Oncostatin-M 209a.a.
2µg
103-09
rhAK1-3
重组人血管抑素K1-3
Recombinant Human Angiostatin K1-3
10µg
103-12
rhEndostatin
重组人血管内皮抑素
Recombinant Human Endostatin
2µg
104-01
rhaFGF
重组人碱性成纤维细胞生长因子--酸性
Recombinant Human Fibroblast Growth Factor- acidic
10µg
104-02
rhbFGF
重组人碱性成纤维细胞生长因子--碱性
Recombinant Human Fibroblast Growth Factor-basic
10µg
104-07
rhKGF-1
重组人角质细胞生长因子-1
Recombinant Human Keratinocye Growth Factor-1
2µg
104-09
rhFGF-9
重组人成纤维细胞生长因子-9
Recombinant Human Fibrobalst Growth Factor-9
5µg
104-10
rhKGF-2
重组人角质细胞生长因子-2
Recombinant Human Keratinocye Growth Factor-2
5µg
104-19
rhFGF-19
重组人成纤维细胞生长因子-19
Recombinant Human Fibrobalst Growth Factor-19
5µg
104-21
rhFGF-21
重组人成纤维细胞生长因子-21
Recombinant Human Fibrobalst Growth Factor-21
5µg
105-01
rhIGF-I
重组人IGF-I
Recombinant Human IGF-I
20µg
105-01B
rHuDES1-3/IGF1
重组人 DES1-3/ 胰岛样生长因子 -1
Recombinant Human DES1-3/ Insulin-Like Growth factor 1
20μg
105-01B3
rhIGF-BP3
重组人 IGF-BP3
Recombinant Human IGF-BP3
5µg
105-03
rhLR3IGF-1
重组人长R3胰岛样生长因子-1
Recombinant Human Long R3 Insulin-like Growth factor-1
20µg
105-04
rhEGF
重组人表皮细胞生长因子
Recombinant Human Epidermal Growth Factor
100µg
105-05
rhVEGF165
重组人血管内皮生长因子165
Recombinant Human VEGF165
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