FITC标记的160kDa内含子结合蛋白抗体
产品名称： FITC标记的160kDa内含子结合蛋白抗体
英文名称： Anti-IBP160/FITC
产品编号： HZ-15530R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-IBP160/FITC Conjugated antibody
FITC标记的160kDa内含子结合蛋白抗体
| 英文名称 | Anti-IBP160/FITC |
| 中文名称 | FITC标记的160kDa内含子结合蛋白抗体 |
| 别 名 | AQR; AQR_HUMAN; aquarius; aquarius homolog (mouse); DKFZp686B23123; fSAP164; functional spliceosome-associated protein 164; IBP160; Intron-binding protein aquarius; Intron-binding protein of 160 kDa; KIAA0560. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 染色质和核信号 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 171kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IBP160 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Subunit: Identified in the spliceosome C complex. Subcellular Location: Nucleus. Note=Localizes to speckle-like regions of the nucleoplasm. Similarity: Belongs to the CWF11 family. Database links: Entrez Gene: 9716 Human Omim: 610548 Human SwissProt: O60306 Human Unigene: 510958 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
内含子结合的剪接体蛋白需要连接前mRNA剪接和SnRNP（小核仁核糖核蛋白）的生物合成。在内含子编码盒C/D小snoRNP的位置依赖组装中起关键作用，snoRNP组装需要拼接。可以通过帮助SnRNA序列的折叠来起作用。以序列独立的方式与前mRNA的内含子结合，在剪接的晚期阶段接触snoRNA和内含子的分枝点(分枝点上游的40个核苷酸)之间的区域。