FITC标记的弥漫性泛细支气管炎相关蛋白1抗体
产品名称： FITC标记的弥漫性泛细支气管炎相关蛋白1抗体
英文名称： Anti-DPCR1/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DPCR1/FITC Conjugated antibody
FITC标记的弥漫性泛细支气管炎相关蛋白1抗体
| 英文名称 | Anti-DPCR1/FITC |
| 中文名称 | FITC标记的弥漫性泛细支气管炎相关蛋白1抗体 |
| 别 名 | bCX105N19.6; Diffuse panbronchiolitis critical region 1; Diffuse panbronchiolitis critical region; Diffuse panbronchiolitis critical region protein 1; DKFZp666O235; DPCR protein; DPCR1; DPCR1_HUMAN; MGC126710; MGC126712; OTTHUMP00000062447; PBLT. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse DPCR1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: DPCR1 is a 517 amino acid single-pass type I membrane protein that exists as 2 alternatively spliced isoforms. Expressed in adult small intestine, uterus, esophagus, lung, kidney, testis, rectum, stomach, cervix and skin, DPCR1 has also been observed in fetal kidney, lung and heart. The gene encoding DPCR1 maps to a region on chromosome 6 that is shared by seven other genes, which have been linked to diffuse panbronchiolitis. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. Function: Detected in lung, esophagus, stomach, rectum, skin, cervix, testis, kidney, uterus and small intestine. Subcellular Location: Membrane. Tissue Specificity: Expressed in fetal heart, kidney and lung. Database links: Entrez Gene: 135656 Human Omim: 613928 Human SwissProt: Q3MIW9 Human Unigene: 631993 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
DPCR1是一种517氨基酸单通道I型膜蛋白，以2种交替剪接的亚型存在。DPCR1在小肠、子宫、食管、肺、肾、睾丸、直肠、胃、宫颈和皮肤中均有表达，在胎儿肾、肺和心脏中也有表达。编码DPCR1的基因定位在6号染色体上的一个区域，该区域由其他7个基因共享，这些基因与弥漫性泛细支气管炎有关。第6染色体包含1亿7000万个碱基对，并包含人类基因组的近6%。6号染色体q臂部分缺失与早期发病的肠癌有关，提示存在癌症易感位点。此外，迟发性皮肤卟啉症、帕金森病、Stickler综合征和双相情感障碍的易感性都与映射到6号染色体的基因有关。