FITC标记的NBPF3蛋白抗体
产品名称： FITC标记的NBPF3蛋白抗体
英文名称： Anti-NBPF3/FITC
产品编号： HZ-19035R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NBPF3/FITC Conjugated antibody
FITC标记的NBPF3蛋白抗体
| 英文名称 | Anti-NBPF3/FITC |
| 中文名称 | FITC标记的NBPF3蛋白抗体 |
| 别 名 | AE2; NBPF3; NBPF3_HUMAN; Neuroblastoma breakpoint family member 3; Protein AE2; Protein SHIIIa4; RP11-293F5.5. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 73kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NBPF3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. DUF1220 copy number variations in human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Feb 2013] Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in testis and fetal heart, as well as in non small cell lung carcinoma and neuroblastoma cell line. Similarity: Belongs to the NBPF family. Contains 5 NBPF domains. Database links: Entrez Gene: 84224 Human SwissProt: Q9H094 Human Unigene: 325422 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是神经母细胞瘤断裂点家族（NBPF）的成员，该家族由几十个最近复制的基因组成，这些基因主要位于人类1号染色体上的片段性复制中。这个基因家族在人类谱系内经历了最大的扩展，并且在较小程度上在灵长类动物中普遍扩展。该基因家族的成员以DUF1220蛋白结构域的重复复制为特征。人类染色体1q21.1区DUF1220拷贝数变异与许多发育和神经遗传学疾病有关，如小脑、巨脑、自闭症、精神分裂症、智力低下、先天性心脏病、神经母细胞等。MA和先天性肾脏和泌尿道异常。一些基因家族成员的表达改变与多种类型的癌症相关。该基因家族含有大量的假基因。[ RefSeq，FEB 2013 ]提供