大鼠小胶质细胞
产品名称: 大鼠小胶质细胞
英文名称: Rat Microglia
产品编号: R1900
产品价格: 0
产品产地: 美国
品牌商标: sciencell
更新时间: 2024-10-30T10:05:13
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上海中乔新舟生物科技有限公司是美国Sciencell公司在中国正规一级代理:
美国ScienCell研究实验室(www.sciencellonline.com)成立于1999年,公司总部位于美国加州的圣地亚哥。主要致力于实验室科研用原代细胞、原代细胞专用培养基、原代细胞无血清培养基、干细胞、干细胞培养基、干细胞无血清培养基的研究和开发,在全球拥有众多客户。在国内销售15年来,很多老师应用其产品发表了高质量的SCI文章,且有着极高的文献引用率。凭借着严格的质控和优秀的产品品质,深受广大科研工作者的信赖。 请登录Sciencell公司官方网站(www.zqxzbio.com或www.sciencellonline.com)以确保购买正规公司产品。
小胶质细胞是中枢神经系统中一种胶质细胞类型,它是神经胶质细胞网不可或缺的重要组成部分。小胶质细胞在大脑实质从早期向成熟阶段发育的过程中被发现。在大脑发育过程中或中枢神经系统受损或受到病理伤害而发生程序性细胞死亡时,小胶质细胞的作用如同大脑中的巨噬细胞。小胶质细胞被认为是大脑免疫监督的主要细胞,向CD4阳性T细胞表达的II类MHC呈递抗原,具有Fc-介导的巨噬作用并与造血和巨噬细胞组织有许多同样的抗原。另外,有大量证据表明作用,在大脑中小胶质细胞通过与神经元和其它胶质细胞共同作用和产生诸如生长因子、细胞因子和其它因子的方式来参与许多生理和病理过程。 推荐培养基:(MM, Cat. No. 1901) Microglia, one of the glial cell types in the CNS, is an important integral component of the neuro-glial cell network [1]. They have been observed in the brain parenchyma from the early stage of development to the mature state. Microglia act as brain macrophages when programmed cell death occurs during brain development or when the CNS is injured or pathologically damaged. Microglia can be considered the main cell in brain immune surveillance, can present antigens in the molecular context of MHC class II expression to CD-4 positive T cells, are capable of Fc-mediated phagocytosis, and share many common antigens with hemopoietic and tissue macrophages [2]. Furthermore, there is accumulating evidence that microglia are involved in a variety of physiological and pathological processes in the brain by interacting with neurons and other glial cells and through production of biologically active substances such as growth factors, cytokines, and other factors [3]. RM is for research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures. Transfer cells directly and immediately from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture is needed for experiments. Dry ice or gel ice. [1] Lee, S. C., Liu, W., Brosnan, C. F. and Dickson, D. W. (1992) Characterization of primary human fetal dissociated central nervous system cultures with an emphasis on microgia. Laboratory Investigation. 67:465-476.
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