RBBP6抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
RBBP6抗体

RBBP6抗体

商家询价

产品名称： RBBP6抗体

英文名称： RBBP6Antibody

产品编号： XY11882-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 RBBP6抗体Applications

In-house applications ELISA, WB, IF     Application not tested? Please see our Guarantee.
Species specificity Human, Mouse; other species not tested.
Images
Prev1NextView more validation data
  • 11882-1-AP;HEK-293 cellsHEK-293 cells were subjected to SDS PAGE followed by western blot with 11882-1-AP(RBBP6 antibody) at dilution of 1:400
  • 11882-1-AP;Transfected HEK-293 cellsTransfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 11882-1-AP( RBBP6 Antibody) at dilution of 1:500
  • 11882-1-AP;HeLa cellsImmunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 11882-1-AP( RBBP6 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in HEK-293 cells, mouse placenta tissue, Transfected HEK-293 cells
Positive IF detected in HeLa cells
Recommended dilution WB : 1:200-1:2000
IF : 1:50-1:500
 RBBP6抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information RBBP6抗体
Immunogen RBBP6 fusion protein ag2484 Full name Retinoblastoma binding protein 6
Calculated molecular
weight		 1792aa,200 kDa Observed molecular 
weight		 200 kDa
GenBank accession 
number		 BC029352 Gene ID (NCBI) 5930
Gene symbol RBBP6 Synonyms DKFZp686P0638, DKFZp761B2423, MY038, P2P R, P2PR, PACT, Protein P2P R, RBBP6, RBQ 1, RBQ1, SNAMA
Background

RBBP6 (retinoblastoma binding protein 6) is a multifunctional protein that interacts with both p53 and pRb and has been implicated in mRNA processing. It has also been identified as a putative E3 ubiquitin ligase due to the presence of a RING finger domain [PMID:18851979]. RBBP6 contains an N-terminal ubiquitin-like domain and a cysteine-rich RING finger-like domain, through which it promotes the ubiquitination of p53 by Hdm2 in an E4-like manner [PMID:17470788]. It is implicated in a diverse set of cellular functions, including mRNA metabolism, regulation of the cell cycle, tumorigenesis, and development [PMID:12938151,17470788]. RBBP6抗体

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