FITC标记的富含亮氨酸重复蛋白26抗体
产品名称： FITC标记的富含亮氨酸重复蛋白26抗体
英文名称： Anti-LRRC26/FITC
产品编号： HZ-18372R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LRRC26/FITC Conjugated antibody
FITC标记的富含亮氨酸重复蛋白26抗体
| 英文名称 | Anti-LRRC26/FITC |
| 中文名称 | FITC标记的富含亮氨酸重复蛋白26抗体 |
| 别 名 | bA350O14.10; CAPC; cytokeratin-associated protein; Cytokeratin-associated protein in cancer; Leucine-rich repeat-containing protein 26; LRC26_HUMAN; Lrrc26. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 细胞膜受体 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LRRC26 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: LRRC26 is a 334 amino acid protein that localizes to the cytoplasm and contains six LRR repeats. Expressed at high levels in normal colon, pancreas, prostate, salivary gland and intestine, LRRC26 is also present in several cancer cell lines, including colon cancer and pancreatic cancer, suggesting an important role in carcinogenesis. Function: Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium. Subcellular Location: Membrane. Cytoplasm; cytoskeleton. Although predicted to be a single-pass type I membrane protein, this protein localizes to the cytoplasm when expressed at high levels. Tissue Specificity: Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines. Similarity: Contains 5 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Database links: Entrez Gene: 389816 Human Omim: 613505 Human SwissProt: Q2I0M4 Human Unigene: 669977 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
LRRC26是定位于细胞质并含有六个LRR重复序列的334个氨基酸蛋白。LRRC26在正常结肠、胰腺、前列腺、唾液腺和肠道中高水平表达，在包括结肠癌和胰腺癌在内的几种癌细胞系中也存在，表明LRRC26在癌症发生中起重要作用。