DDX19B,解旋酶DEAD5抗体

产品编号HZ-3764R
英文名称DDX19B
中文名称解旋酶DEAD5抗体
别 名DDX19B; Dbp5; DDX19; DEAD box protein 19B; DEAD box RNA helicase DEAD5; helicase DEAD5; DD19B_HUMAN; ATP-dependent RNA helicase DDX19B; DEAD box RNA helicase DEAD5; DBP5; TDBP.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 神经生物学 激酶和磷酸酶
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
DDX19B,解旋酶DEAD5抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
细胞定位细胞核 细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DDX19B
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DDX19B,解旋酶DEAD5抗体PubMedPubMed
产品介绍background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function:
ATP-dependent RNA helicase involved in mRNA export from the nucleus.

Subunit:
Interacts with NUP214.

Subcellular Location:
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.

Similarity:
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.

Gene ID:
11269

DDX19B,解旋酶DEAD5抗体Database links:
Entrez Gene: 11269 Human
Entrez Gene: 517438 Cow
Entrez Gene: 234733 Mouse
Entrez Gene: 690693 Rat
Omim: 605812 Human
SwissProt: Q3ZBV2 Cow
SwissProt: Q9UMR2 Human
Unigene: 221761 Human
Unigene: 482176 Mouse
Unigene: 60026 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.