FITC标记的白细胞介素31抗体
产品名称： FITC标记的白细胞介素31抗体
英文名称： Anti-IL-31/FITC
产品编号： HZ-10069R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-IL-31/FITC Conjugated antibody
FITC标记的白细胞介素31抗体
| 产品编号 | bs-10069R-FITC |
| 英文名称 | Anti-IL-31/FITC |
| 中文名称 | FITC标记的白细胞介素31抗体 |
| 别 名 | Interleukin-31; 1700013B14RIK; IL31; interleukin-31 precursor; IL 31; IL-31; IL31_HUMAN; IL31_MOUSE; Interleukin 31. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 16kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-31 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008] Function: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. Subcellular Location: Secreted. Tissue Specificity: Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea. Database links: Entrez Gene: 386653 Human Entrez Gene: 76399 Mouse Omim: 609509 Human SwissProt: Q6EBC2 Human SwissProt: Q6EAL8 Mouse Unigene: 569071 Human Unigene: 75049 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. IL-31是一种新型T细胞衍生的细胞因子,其功能受体复合物是由IL-31RA/GPL/GLM R和OSMR组成的异二聚体。它们在过敏性和非过敏性疾病中起重要作用。 |
IL31主要由活化的Th2型T细胞组成，与由IL31 RA（MIM 609510）和OSMR（MIM 601743）组成的异源二聚体受体相互作用，其在上皮细胞和角质形成细胞上组成性表达。IL31可能参与促进过敏性皮肤疾病和调节其他过敏性疾病，如哮*（狄龙等，2004年[PubMed 151848 96]）。