Iterative Crystallography Service:Polyadenylate-binding Protein 2
产品名称: Iterative Crystallography Service:Polyadenylate-binding Protein 2
英文名称: Iterative Crystallography Service:Polyadenylate-binding Protein 2
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http://www.creative-biostructure.com/Iterative-crystallography/Iterative-crystallography-CBCRY37.htm
Cat. No. |
CBCRY37 |
|
Background |
Poly(A) binding protein, nuclear 1, also known as PABPN1, is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. |
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Molecular description |
Protein Classification |
RNA binding protein |
Structure Weight |
43445.20 Da |
|
Polymer |
1 |
|
Molecule |
Polyadenylate-binding protein 2 |
|
Chain Length |
96 amino acids |
|
Crystal Description |
PDB ID |
|
MMDB ID |
||
Source |
E.coli |
|
Method |
X-Ray Diffraction |
|
Resolution |
2.82Å |
|
Gene information |
Gene Name |
|
Synonyms |
OPMD; PAB2; PABP2; poly(A) binding protein 2; poly(A) binding protein II; poly(A) binding protein, nuclear 1 |
|
UniProt ID |
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GeneID |
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Chromosome Location |
14q11.2-q13 |
|
Function |
nucleotide binding; nucleic acid binding; RNA binding; protein binding |
|
Reference |
Ge, H., Zhou, D., Tong, S., Gao, Y., Teng, M., Niu, L. (2008) Crystal structure and possible dimerization of the single RRM of human PABPN1 Proteins 71: 1539-1545 |