FITC标记的Endokinin-A/B抗体
产品名称： FITC标记的Endokinin-A/B抗体
英文名称： Anti-Endokinin-A/B/FITC
产品编号： HZ-16470R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Endokinin-A/B/FITC Conjugated antibody
FITC标记的Endokinin-A/B抗体
| 英文名称 | Anti-Endokinin-A/B/FITC |
| 中文名称 | FITC标记的Endokinin-A/B抗体 |
| 别 名 | EK; Endokinin; HK 1; EKA/B; HK1; TKN4_HUMAN; Preprotachykinin C; TAC4; Tachykinin 4 (hemokinin); Tachykinin 4; Endokinin-A. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 5.0kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Hemokinin 1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Hemokinin 1 are from the Tachykinins family of proteins that are active peptides which excite neurons. They evoke behavioral responses and are potent vasodilators and secretagogues. Hemokinin 1 involved in contraction (directly or indirectly) of many smooth muscles. Hemokinin 1is cleaved in to three short peptides Edokinin A,B,C. Endokinin A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with Endokinin C. Endokinin A/B reduces arterial blood pressure and increases sperm motility. Subcellular Location: Secreted. Tissue Specificity: Expressed at low levels in the uterus of both pregnant and non-pregnant women. Isoform 1 is found only in the adrenal gland and fetal liver. Isoform 2 is found in heart, liver, bone marrow, prostate, adrenal gland and testis. Isoform 3 and isoform 4 are expressed predominantly in adrenal gland and placenta. Similarity: Belongs to the tachykinin family. Database links: Entrez Gene: 255061 Human Omim: 607833 Human SwissProt: Q86UU9 Human Unigene: 652130 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是tachykinin家族神经递质编码基因的成员。速激肽蛋白裂解成小的分泌肽，激活受体蛋白家族的成员。该基因的产物优先激活速激肽受体1，并被认为调节外周内分泌和旁分泌功能，包括血压、免疫系统和内分泌腺的分泌。该基因的产物缺乏在其他速激肽蛋白中发现的二碱基切割位点。因此，在体内生成的卵裂产物的性质尚待确定。该基因已发现编码不同亚型的多个转录变体。[ RefSeq，JUL 2008 ]