FITC标记的真核翻译起始因子2C3抗体
产品名称： FITC标记的真核翻译起始因子2C3抗体
英文名称： Anti-Argonaute 3/FITC
产品编号： HZ-12517R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Argonaute 3/FITC Conjugated antibody
FITC标记的真核翻译起始因子2C3抗体
| 英文名称 | Anti-Argonaute 3/FITC |
| 中文名称 | FITC标记的真核翻译起始因子2C3抗体 |
| 别 名 | eIF2C3; Argonaute 3/eIF2C 3; 5730550L01Rik; Ago 3; Ago3; AGO3_HUMAN; argonaute 3; Argonaute3; eIF 2C 3; eIF-2C 3; eIF2C 3; Eif2c3; eIF2C3; EIF2C3 protein; Eukaryotic translation initiation factor 2C 3; Eukaryotic translation initiation factor 2C3; FLJ12765; hAgo3; MGC86946; Protein argonaute-3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Danio rerio |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 97kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Argonaute 3/eIF2C3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Subunit: Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H. Subcellular Location: Cytoplasm. Similarity: Belongs to the argonaute family. Ago subfamily. Contains 1 PAZ domain. Contains 1 Piwi domain. Database links: Entrez Gene: 192669 Human Entrez Gene: 214150 Mouse Entrez Gene: 313593 Rat Omim: 607355 Human SwissProt: Q9H9G7 Human SwissProt: Q8CJF9 Mouse Unigene: 657659 Human Unigene: 440915 Mouse Unigene: 482388 Mouse Unigene: 483093 Mouse Unigene: 92025 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码Argonaute家族成员，它们在RNA干扰中起作用。编码的蛋白质是高度碱性的，包含PAZ结构域和PIWI结构域，并且可能在短干扰RNA介导的基因沉默中发挥作用。该基因位于染色体1上，与精氨酸转运蛋白4和真核翻译起始因子2C、1等家族成员紧密连锁。已经鉴定了两个编码不同亚型的转录变体。[ RefSeq，JUL 2008 ]