FITC标记的多聚腺苷酸结合蛋白相互作用蛋白2抗体
产品名称： FITC标记的多聚腺苷酸结合蛋白相互作用蛋白2抗体
英文名称： Anti-PAIP2/FITC
产品编号： HZ-21007R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PAIP2/FITC Conjugated antibody
FITC标记的多聚腺苷酸结合蛋白相互作用蛋白2抗体
| 英文名称 | Anti-PAIP2/FITC |
| 中文名称 | FITC标记的多聚腺苷酸结合蛋白相互作用蛋白2抗体 |
| 别 名 | PABP-interacting protein 2; PAIP-2; PAIP2; PAIP2_HUMAN; poly(A) binding protein interacting protein 2; Poly(A)-binding protein-interacting protein 2; Polyadenylate-binding protein-interacting protein 2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转录调节因子 结合蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 15kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PAIP2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: PAIP2 (Poly(A) Binding Protein Interacting Protein 2) is a Protein Coding gene. Among its related pathways are Translational Control and TGF-Beta Pathway. GO annotations related to this gene include mRNA binding and translation repressor activity. An important paralog of this gene is PAIP2B. Function: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. Subunit: Interacts with the RRM1-RRM2 and C-terminus regions of PABPC1 in a 1:1 stoichiometry. Interacts with EIF4A. Subcellular Location: Cytoplasm. Similarity: Belongs to the PAIP2 family. Database links: Entrez Gene: 416187 Chicken Entrez Gene: 536619 Cow Entrez Gene: 51247 Human Entrez Gene: 67869 Mouse Entrez Gene: 361309 Rat Omim: 605604 Human SwissProt: Q5ZJS6 Chicken SwissProt: Q3ZC67 Cow SwissProt: Q9BPZ3 Human SwissProt: Q9D6V8 Mouse SwissProt: Q6AXZ0 Rat Unigene: 396644 Human Unigene: 126534 Mouse Unigene: 1073 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
PAIP2（Poly（a）结合蛋白相互作用蛋白2）是蛋白质编码基因。其相关途径是翻译控制和TGF-β途径。与此基因相关的注释包括mRNA结合和翻译阻遏活性。这个基因的一个重要旁系同源物是PAIP2b。