FITC标记的磷酸化色氨酸羟化酶抗体
产品名称： FITC标记的磷酸化色氨酸羟化酶抗体
英文名称： Anti-phospho-TPH (Ser260)/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-phospho-TPH (Ser260)/FITC Conjugated antibody
| FITC标记的磷酸化色氨酸羟化酶抗体 |
| 英文名称 | Anti-phospho-TPH (Ser260)/FITC |
| 中文名称 | FITC标记的磷酸化色氨酸羟化酶抗体 |
| 别 名 | Tph1(phospho S260); TPH (phospho Ser260); p-TPH (Ser260); MGC119994; TPH 1; TPH; TPH1; TPRH; Tryptophan 5 hydroxylase 1; Tryptophan 5 monooxygenase 1; Tryptophan 5 monooxygenase; Tryptophan hydroxylase 1; Tryptophan 5-hydroxylase 1; TPH1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 免疫学 神经生物学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human TPH around the phosphorylation site of Ser260 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]. Subunit: Homotetramer (By similarity). Tissue Specificity: Isoform 2 seems to be less widely expressed than isoform 1. Similarity: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. Contains 1 ACT domain. Database links: Entrez Gene: 7166 Human Entrez Gene: 21990 Mouse Entrez Gene: 24848 Rat Omim: 191060 Human SwissProt: P17752 Human SwissProt: P17532 Mouse SwissProt: P09810 Rat Unigene: 591999 Human Unigene: 248684 Mouse Unigene: 94788 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 色氨酸在脑中首先由色氨酸羟化酶(tryoptophan hydroxylase)催化生成5羟色氨酸(5hydroxytryptophan)，再经脱羧酶作用生成5羟色胺，色氨酸羟化酶（TPH）是5-HT生物合成的限速酶，因此，色氨酸羟化酶的缺少可导致5-羟色胺的含量下降。色氨酸羟化酶主要在肝脏内代谢 |
该基因编码芳香族氨基酸羟化酶家族的成员。编码的蛋白质催化血清素生物合成中的第一和限速步骤，5-羟色胺是一种重要的和神经递质。该基因的突变与多种疾病和疾病的风险升高有关，包括精神分裂症、躯体焦虑、愤怒相关特征、双相情感障碍、**行为、成瘾等。[ RefSeq，APR 2009 ]提供。