FITC标记的FAM86A蛋白抗体
产品名称： FITC标记的FAM86A蛋白抗体
英文名称： Anti-FAM86A/FITC
产品编号： HZ-16019R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FAM86A/FITC Conjugated antibody
FITC标记的FAM86A蛋白抗体
| 英文名称 | Anti-FAM86A/FITC |
| 中文名称 | FITC标记的FAM86A蛋白抗体 |
| 别 名 | FA86A_HUMAN; Protein FAM86A. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 37kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FAM86A |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. FAM86A and FAM86B2 are 330 amino acid proteins that belongs to the FAM86 family. The gene encoding FAM86A maps to human chromosome 16 whereas the gene encoding FAM86B2 maps to human chromosome 8. Subunit: Interacts with FAM86B2 and FAM86C1. Subcellular Location: Cytoplasm. Similarity: Belongs to the FAM86 family. Database links: Entrez Gene: 196483 Human SwissProt: Q96G04 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
染色体16在大约9千万碱基对中编码900多个基因，占人类细胞DNA的近3%，并且与多种遗传病有关。GAN基因位于16号染色体上，随着突变，可能导致巨大的轴突神经病变，一种神经系统紊乱，特征是随着生长而增加功能障碍。罕见的Rubinstein-Taybi综合征也与染色体16有关，尽管是通过CREBBP基因编码的关键CREB结合蛋白。Rubinstein Taybi的症状包括精神发育迟滞和肿瘤生长和白细胞肿瘤的易感性。Crohn病是通过NOD2基因与16号染色体相关的胃肠道炎症状态。系统性红斑狼疮和许多其它与染色体16的着丝粒周区相关的自身免疫性疾病导致SLC5A11被鉴定为潜在的自身免疫调节剂。FAM86A和FAM86B2是属于FAM86家族的330个氨基酸。编码FAM86A的基因映射到人类16号染色体，而编码FAM86B2的基因映射到人类8号染色体。