FITC标记的染色体脆弱性相关基因抗体
产品名称： FITC标记的染色体脆弱性相关基因抗体
英文名称： Anti-ATAD5/FITC
产品编号： HZ-7656R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ATAD5/FITC Conjugated antibody
FITC标记的染色体脆弱性相关基因抗体
| 英文名称 | Anti-ATAD5/FITC |
| 中文名称 | FITC标记的染色体脆弱性相关基因抗体 |
| 别 名 | ATPase family AAA domain containing 5; C17orf41; chromosome fragility associated gene 1; FRAG1; Putative uncharacterized protein Fragment. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 染色质和核信号 细胞凋亡 细胞周期蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 203kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ATAD5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: ATAD5 is a homolog of a subunit of RFC (replication factor C) and has been shown to be down-regulated in response to replicative stress. ATAD5 may play a role in the surveillance of DNA damage and the cell’s decision to survive or activate apoptosis. Subunit: "Interacts with RB1 predominantly in G1 phase via its LXCXE motif. Interacts with RAD9A in growing cells. The interaction with RAD9A is reduced after exposure to DNA replication-inhibiting agents. Subcellular Location: Nucleus. Similarity: Belongs to the AAA ATPase family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
ATAD5是RFC（复制因子C）的亚基的同源物，并且已被证明是响应复制应激而下调的。ATAD5可能在DNA损伤监测和细胞存活或激活凋亡的决定中发挥作用。