ADCY2,腺苷酸环化酶2抗体

产品编号HZ-3920R
英文名称ADCY2
中文名称腺苷酸环化酶2抗体
别 名adenylate cyclase 2; HBAC2; KIAA1060; type II adenylate cyclase; ADCY2_HUMAN.
规格价格0.1ml 0.2ml 
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 信号转导 生长因子和激素 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
ADCY2,腺苷酸环化酶2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量124kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ADCY2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ADCY2,腺苷酸环化酶2抗体PubMedPubMed
产品介绍background:
ADCY2 is a membrane-bound, calmodulin-insensitive adenylyl cyclase.

Function:
This is a membrane-bound, calmodulin-insensitive adenylyl cyclase.

Subunit:
Interacts with RAF1.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in brain.

Post-translational modifications:
Phosphorylated by RAF1.

Similarity:
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains.

ADCY2,腺苷酸环化酶2抗体Gene ID:
108

Database links:
Entrez Gene: 108 Human
Entrez Gene: 210044 Mouse
Entrez Gene: 81636 Rat
Omim: 103071 Human
SwissProt: Q08462 Human
SwissProt: Q80TL1 Mouse
SwissProt: P26769 Rat
Unigene: 10731 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片

Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-ADCY2 Polyclonal Antibody, Unconjugated(bs-3920R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining