FITC标记的锌指蛋白639抗体
产品名称： FITC标记的锌指蛋白639抗体
英文名称： Anti-ZNF639/FITC
产品编号： HZ-18488R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ZNF639/FITC Conjugated antibody
FITC标记的锌指蛋白639抗体
| 英文名称 | Anti-ZNF639/FITC |
| 中文名称 | FITC标记的锌指蛋白639抗体 |
| 别 名 | ZNF 639; 6230400O18Rik; ANC 2H01; ANC_2H01; MGC157200; OTTHUMP00000212173; OTTHUMP00000212174; OTTHUMP00000212175; OTTHUMP00000212195; OTTHUMP00000212197; ZASC1; Zfp639; Zinc finger amplified in esophageal squamous cell carcinomas 1; Zinc finger protein 639; Zinc finger protein ANC 2H01; Zinc finger protein ANC_2H01; Zinc finger protein ZASC1; ZN639_HUMAN; ZNF 639; Znf639; ZNF639 zinc finger protein 639. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 56kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF639 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: ZNF639 is a 485 amino acid protein that localizes to the nucleus and contains five C2H2-type zinc fingers. One of several members of the Krueppel C2H2-type zinc-finger family, ZASC1 is thought to be involved in transcriptional regulation. The gene encoding ZASC1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. Function: Binds DNA and may function as a transcriptional repressor. Subunit: Interacts with CTNNA2. Subcellular Location: Nucleus. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 8 C2H2-type zinc fingers. Database links: Entrez Gene: 51193 Human Entrez Gene: 523536 Cow Entrez Gene: 67778 Mouse Entrez Gene: 683504 Rat SwissProt: A5PK30 Cow SwissProt: Q9UID6 Human SwissProt: Q99KZ6 Mouse SwissProt: Q5PPG4 Rat Unigene: 632578 Human Unigene: 285620 Mouse Unigene: 116062 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
ZNF639是一个485个氨基酸的蛋白质，定位于细胞核，含有五个C2H2型锌指。作为Krueppel C2H2型锌指家族的几个成员之一，ZASC1被认为参与转录调节。编码ZASC1的基因定位于人类3号染色体，其中包含1100多个基因，包括趋化因子受体（CKR）基因簇和各种人类癌症相关基因位点。染色体3上的主要抑癌基因包括凋亡介质RASSF1、细胞迁移调节因子HYAL1和血管生成抑制因子SEMA3B。F与3号染色体相关的多种遗传疾病。