FITC标记的海马丰富基因转录蛋白1抗体
产品名称: FITC标记的海马丰富基因转录蛋白1抗体
英文名称: Anti-HIAT1/FITC
产品编号: HZ-
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-20
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Rabbit Anti-HIAT1/FITC Conjugated antibody
FITC标记的海马丰富基因转录蛋白1抗体
英文名称 | Anti-HIAT1/FITC |
中文名称 | FITC标记的海马丰富基因转录蛋白1抗体 |
别 名 | Hippocampus abundant gene transcript 1; Hippocampus abundant transcript; Hippocampus abundant transcript 1; Putative tetracycline transporter like protein; Tetracycline transporter like prot; MGC144858; rCG_28876; DKFZp564L0864; HIAT1_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Cow, Horse, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 53kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HIAT1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The Major facilitator superfamily consists of presumed carbohydrate transporters with 10-12 membrane-spanning domains. Belonging to the facilitator superfamily, HIAT1 is a 490 amino acid multi-pass membrane protein that may function as a sugar transporter and is expressed in adult and embryonic brain. The HIAT1 gene was first observed while analyzing for active genes in neonatal mouse hippocampus. The gene encoding HIAT1 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. Stickler syndrome, Parkinsons, schizophrenia, familial adenomatous polyposis, Gaucher disease and Usher syndrome are also associated with chromosome 1. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Similarity: Belongs to the major facilitator superfamily. Database links: Entrez Gene: 64645 Human Entrez Gene: 15247 Mouse Entrez Gene: 100134827 Rat SwissProt: Q96MC6 Human SwissProt: P70187 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
主要促性腺超家族由推测的10-12个跨膜结构域的碳水化合物转运蛋白组成。HIT1属于促性腺超家族,是一种490氨基酸多通道膜蛋白,可作为糖转运蛋白并在和胚胎脑中表达。HIT1基因在新生小鼠海马中的活性基因分析中首次被观察到。HIT1基因编码到人类染色体1,最大的人类染色体跨越2亿6000万个碱基对,占人类基因组的8%。在1号染色体上有大约3000个基因,并且考虑到大量的基因,也有大量的与染色体1相关的疾病。值得注意的是,罕见的老年性疾病Hutchinson Gilford早老症与编码lamin A. Stickler综合征的LMNA基因、帕金森氏症、精神分裂症、家族性腺瘤性息肉病、高雪氏病和Aukes综合征相关,也与1号染色体有关。