Anti-RFTN2/FITC Conjugated抗体-抗体-抗体-生物在线
上海沪震实业有限公司
Anti-RFTN2/FITC Conjugated抗体

Anti-RFTN2/FITC Conjugated抗体

商家询价

产品名称: Anti-RFTN2/FITC Conjugated抗体

英文名称: Anti-RFTN2/FITC

产品编号: YB--8500R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:24:20

使用范围: 科研使用

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 Anti-RFTN2/FITC Conjugated抗体

产品编号 YB-8500R-FITC
英文名称 Anti-RFTN2/FITC
中文名称 FITC标记的RFTN2蛋白抗体
别    名 Raft-linking protein 2; Raftlin-2; Rftn2; RFTN2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RFTN2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
产品介绍 background:
Membrane microdomains known as lipid rafts are implicated in B-cell activation during B-cell receptor (BCR) signal initiation. Raftlin-2, also designated RFTN2 (raftlin family member 2) or raft-linking protein 2, is a 501 amino acid cell membrane protein that is essential for raft cell assembly and maintenance. A lipid anchor protein, Raftlin-2 belongs to the raftlin family and is encoded by a gene that maps to human chromosome 2q33.1 and mouse chromosome 1 C1.2. Human chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene.

Subcellular Location:
Cell membrane; Lipid-anchor (By similarity). 

Similarity:
Belongs to the raftlin family.

Database links:
UniProtKB/Swiss-Prot: Q52LD8.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicatioNS