FITC标记的NBEAL1蛋白抗体
产品名称： FITC标记的NBEAL1蛋白抗体
英文名称： Anti-NBEAL1/FITC
产品编号： HZ-19216R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NBEAL1/FITC Conjugated antibody
FITC标记的NBEAL1蛋白抗体
| 英文名称 | Anti-NBEAL1/FITC |
| 中文名称 | FITC标记的NBEAL1蛋白抗体 |
| 别 名 | neurobeachin-like 1; A530083I02Rik; ALS2CR16; ALS2CR17; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 16; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 17; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein; Beach; FLJ26555; MGC164581; MGC168834; NBEAL 1; NBEAL1; Neurobeachin like protein 1; OTTHUMP00000205117. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 307 , 151kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NBEAL1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: NBEAL1 is a 2,694 amino acid protein that belongs to the WD repeat Neurobeachin family. While highly expressed in kidney, brain, prostate and testis, NBEAL1 is also found at low levels in peripheral blood leukocytes, small intestine, ovary and colon. NBEAL1 contains one BEACH domain and two WD repeats, and undergoes alternative splicing to produce two isoforms. The gene encoding NBEAL1 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. Function: Neurobeachin-like 1 belongs to the WD repeat neurobeachin family. It contains 1 BEACH domain and 2 WD repeats. Neurobeachin-like 1 is highly expressed in brain, kidney, prostate and testis and weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. It may be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast. Tissue Specificity: Highly expressed in brain, kidney, prostate and testis. Weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. May be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast. Similarity: Belongs to the WD repeat neurobeachin family. Contains 1 BEACH domain. Contains 1 BEACH-type PH domain. Contains 2 WD repeats. Database links: Entrez Gene: 65065 Human Omim: 609816 Human SwissProt: Q6ZS30 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
NBEAL1是属于WD重复Neurobeachin家族的2694氨基酸蛋白。虽然NBEAL1在肾脏、脑、前列腺和睾丸中高度表达，但在外周血白细胞、小肠、卵巢和结肠中也低表达。NBEAL1包含一个滩域和两个WD重复，并经历选择性剪接产生两种异构体。编码NBEAL1的基因定位于人类2号染色体，由2.37亿个碱基组成，编码1400多个基因，约占人类基因组的8%。许多遗传疾病与第2染色体上的基因相关，包括小丑鱼鳞病、谷固醇血症和Alstr鰉综合征。