ATP6V0A4抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ATP6V0A4抗体

ATP6V0A4抗体

商家询价

产品名称： ATP6V0A4抗体

英文名称： ATP6V0A4Antibody

产品编号： XY21570-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 ATP6V0A4抗体

Applications
Tested Applications: ELISA, WB, IHC
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in Mouse kidney tissue
Positive IHC detected in Human renal cell carcinoma tissue, human gliomas tissue
Recommended dilution WB : 1:200-1:1000
IHC : 1:20-1:200
 ATP6V0A4抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 21570-1-AP;mouse kidney tissuemouse kidney tissue were subjected to SDS PAGE followed by western blot with 21570-1-AP( ATP6V0A4 Antibody) at dilution of 1:300
  • 21570-1-AP;human renal cell carcinoma tissueImmunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using 21570-1-AP( ATP6V0A4 Antibody) at dilution of 1:50 (under 10x lens)
  • 21570-1-AP;human renal cell carcinoma tissueImmunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using 21570-1-AP( ATP6V0A4 Antibody) at dilution of 1:50 (under 40x lens)
Product Information ATP6V0A4抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: ATP6V0A4 fusion protein ag16095 Full Name: ATPase, H+ transporting, lysosomal V0 subunit a4
Caculated Molecular
Weight:		 840aa,96 kDa Observed Molecular 
Weight:		  
GenbankNo BC109305 GeneID: 50617
Symbol ATP6V0A4 Synonyms A4, ATP6N1B, ATP6N2, ATP6V0A4, RDRTA2, RTA1C, RTADR, STV1, V ATPase 116 kDa isoform a4, VPH1, VPP2
Background

The ATP6V0A4 is a component of vacuolar-H+ATPase (V-ATPase) which is a multi-subunit enzyme that couples ATP hydrolysis to proton pumping across membranes. The V-ATPases are comprised of two major parts, the cytosolic V1 domain involved in ATP-binding and subsequent hydrolysis, and the membrane-associated V0 domain responsible for proton translocation. The V0 domain is composed of five subunits: a, c, c', c'' and d. The 'a' subunit of V0 domain has four isoforms : a1-a4. It has been found that mutations in ATP6V0A4(a4) are associated with distal renal tubular acidosis(dRTA) combined in some cases with progressive hearing loss leading to sensorineural deafness. This antibody was generated against the internal region of human ATP6V0A4 and is predicted to detect the a4 isoform only. ATP6V0A4抗体

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