NMS,神经调节肽S抗体

产品编号HZ-11443R
英文名称NMS
中文名称神经调节肽S抗体
别 名Neuromedin S; Neuromedin-S; NeuromedinS; Nms; NMS_HUMAN; Prepro NMS.
说 明 书0.1ml 0.2ml
研究领域肿瘤 心血管 神经生物学 信号转导 生长因子和激素 新陈代谢
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
NMS,神经调节肽S抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量4kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Neuromedin S
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
NMS,神经调节肽S抗体PubMedPubMed
产品介绍background:
NMS is a 153 amino acid secreted protein that belongs to the NmU family. NMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. The gene that encodes NMS consists of approximately 12,799 bases and maps to human chromosome 2q11.2. Consisting of 237 million bases and encoding over 1,400 genes, chromosome 2 makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8.

Function:
NMS (neuromedin S) is a 36-amino acid neuropeptide specifically expressed in the suprachiasmatic nucleus (SCN) of the hypothalamus. NMS shares a C-terminal core structure with NMU. NMS mRNA is highly expressed in the central nervous system, spleen and testis. NMS may be implicated in the regulation of circadian rhythms and feeding behavior.

Subcellular Location:
Secreted.

Similarity:
Belongs to the NmU family.

Gene ID:
129521

Database links:
Entrez Gene: 129521 Human
SwissProt: Q5H8A3 Human
Unigene: 567676 Human

NMS,神经调节肽S抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.