FITC标记的腺苷受体A3抗体
产品名称： FITC标记的腺苷受体A3抗体
英文名称： Anti-Adenosine A3 Receptor/FITC
产品编号： HZ-1225R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： Flow-Cyt=1:50-200 IF=1:50-200
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Rabbit Anti-Adenosine A3 Receptor/FITC Conjugated antibody
FITC标记的腺苷受体A3抗体
| 英文名称 | Anti-Adenosine A3 Receptor/FITC |
| 中文名称 | FITC标记的腺苷受体A3抗体 |
| 别 名 | adenosine A3 receptor; A3AR; AD 026; AD026; ADORA 3; ADORA3; bA552M11.5; RP11 552M11.7; TGPCR1; adenosine receptor A3 isoform 1; adenosine receptor A3 isoform 2; AA3R_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 神经生物学 细胞膜受体 G蛋白偶联受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | Flow-Cyt=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ADORA3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Function: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction. Subcellular Location: Cell membrane. Post-translational modifications: Phosphorylation on Ser-317 may be crucial for rapid desensitization. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 403805 Dog Entrez Gene: 140 Human Entrez Gene: 606753 Pig Omim: 600445 Human SwissProt: Q28309 Dog SwissProt: P33765 Human SwissProt: Q6P2N6 Human Unigene: 281342 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ADORA-3(腺苷受体A3)属于G蛋白偶联受体家族，在腺苷调节细胞活力和生长中起关键作用，并且在很多肿瘤中表达增高，A3AR可能成为肿瘤诊断标志物和治疗靶点 |
该基因编码属于腺苷受体家族的蛋白质，它是G蛋白偶联受体，参与多种细胞内信号途径和生理功能。该基因编码的受体介导了心肌缺血时持续的心脏保护功能，参与抑制中性粒细胞介导的组织损伤中的中性粒细胞脱颗粒，参与神经保护和神经退行性作用，也可能参与神经保护作用。介导细胞增殖和细胞死亡。该基因已发现编码不同亚型的多个转录变体。[ RefSeq，JUL 2008 ]提供。