FITC标记的糖脂转移蛋白结构域2抗体
产品名称： FITC标记的糖脂转移蛋白结构域2抗体
英文名称： Anti-GLTPD2/FITC
产品编号： HZ-9557R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GLTPD2/FITC Conjugated antibody
FITC标记的糖脂转移蛋白结构域2抗体
| 产品编号 | bs-9557R-FITC |
| 英文名称 | Anti-GLTPD2/FITC |
| 中文名称 | FITC标记的糖脂转移蛋白结构域2抗体 |
| 别 名 | glycolipid transfer protein domain-containing protein 2; Glycolipid transfer protein domain containing 2; GLTD2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GLTPD2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The GLTP (glycolipid transfer protein) superfamily is defined by a unique lipid transfer/binding fold (GLTP fold) that accelerate glycolipid intermembrane transfer. GLTPD2 is a 291 amino acid protein that belongs to the GLTP family. The gene encoding GLTPD2 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth are both linked to mutations on chromosome 17. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. Similarity: Belongs to the GLTP family. Database links: Entrez Gene: 388323 Human SwissProt: A6NH11 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
GLTP（糖脂转移蛋白）超家族由独特的脂质转移/结合折叠（GLTP折叠）来定义，从而加速糖脂跨膜转移。GLTPD2是属于GLTP家族的291个氨基酸。编码GLTPD2的基因映射到人类17号染色体，其包含超过2.5%的人类基因组并编码超过1200个基因。两个关键的肿瘤抑制基因与17号染色体、p53和BRCA1有关。p53表达的异常或丢失与恶性细胞生长和Li Fraumeni综合征有关。神经纤维瘤病是一种以神经和表皮损伤为特征的疾病，Schwann细胞的生长失调与第17号染色体上的突变有关。亚力山大病、Bito-Hog Dube综合征和Cavava病也与17号染色体有关。